S2CID 20350330
One confounding factor is the complexity of antioxidants, referred to by Halliwell [6] as the antioxidant paradox, or the situation in which antioxidants such as glutathione can possess prooxidant activity causing a hormetic effect enabling the body to bolster its endogenous antioxidant defenses
Of late, multiple transcription factors such as TFAP2C, p53, AP-1, STAT, Nrf2, HIF-1, and C/EBP have been linked with the transcriptional regulation of seleno-GPxs [8, 21,22,23,24]
Folic acid is not a substitute for vitamin B12 although it may improve vitamin B12 deficient megaloblastic anemia
"Glutathione S -transferase measurements and liver disease in man"
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