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Tissue Eng B Rev 17:165176 Lovric-Bencic M, Sikiric P, Hanzevacki JS, Seiwerth S, Rogic D, Kusec V, Aralica G, Konjevoda P, Batelja L, Blagaic AB (2004) Doxorubicine-congestive heart failure-increased big endothelin-1 plasma concentration: reversal by amlodipine, losartan, and gastric pentadecapeptide BPC157 in rat and mouse

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PRPP is an intermediate in purine nucleotide synthesis, generated from ribose 5-phosphate from the pentose phosphate pathway 21

However, some individualswhether due to conditions like pernicious anemia, gastrointestinal disorders, or the effects of certain surgeriesmay have trouble absorbing enough B12 from food or oral supplements