Research suggests it can upregulate genes involved in: Tissue repair Anti-inflammatory responses Cellular regeneration At the same time, it may downregulate genes associated with oxidative stress and tissue breakdown
Cisplatin caused a strong viability decrease of KISPIDMG-105 (IC 50 = 0.05 M) and had only a minimal effect on the BBB (IC 50 = 13.36 M) at potentially therapeutic concentrations
Users considering its use should exercise caution, as most data derive from preclinical studies and anecdotal reports
Cell Rep 32:107987 Michalski A, Damoc E, Hauschild JP, Lange O, Wieghaus A, Makarov A, Nagaraj N, Cox J, Mann M, Horning S (2011) Mass spectrometry-based proteomics using Q Exactive, a high-performance benchtop quadrupole Orbitrap mass spectrometer
Kerner, J
P362+364: Take off contaminated clothing and wash it before reuse