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A common feature to all complexes is a water-mediated interaction between the backbone carbonyl from E238 and the peptides backbone on position +3 (Supplementary Fig

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Moisture can promote hydrolysis (chemical breakdown due to water), and oxygen may contribute to oxidation in susceptible peptide sequences (Sigma-Aldrich, 2023b)

It is synthesized in our cells and primarily stored in the liver, where it plays a crucial role in detoxification and the neutralization of free radicals

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In fact, one study noted that the peptide has a long history of safe use in wound healing and skin care