In a rat model of chronic pneumoconiosis induced by intratracheal injection of quartz powder, catalpol promotes mitochondrial biogenesis through the peroxisome proliferator-activated receptor- coactivator-1 alpha (PGC-1)/nuclear respiratory factor 1 (NRF1) and Transcription Factor A (TFAM) pathways, enhancing mitochondrial function in skeletal muscle, reducing muscle atrophy, and improving exercise capacity (Liu W
During acute wound healing, immune cells are required to eliminate pathogens and prevent infection at the wound site, and ROS play an essential role in this function 94 (Fig
Your GP will manage your B12 treatment programme, which includes regular blood tests to monitor your levels and ensure the dosage and frequency of your injections are appropriate
and 3) activation of the AMPK/PGC-1 /UCP2 axis to improve mitochondrial respiratory efficiency, thereby establishing a comprehensive regulatory framework spanning gene expression to organelle function ( 5.10 Quinones Quinone metabolites, as emerging stars in the field of NAFLD therapy, are reshaping the treatment paradigms for metabolic diseases
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Marchand WR, Yurgelun-Todd D
