first demonstrated in transgenic zebrafish that mitochondrial DNA polymerase and ETC activity are critical for neutrophil motility, highlighting mitochondrial functional integrity as essential for granulocyte migration [118]
This is partially mediated by the MAPK and PI3K/Akt pathways, which are implicated in cell survival and glucose uptake (52)
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The data was then interpreted and discussed, included into specific databases, where correlations and statistics were performed, in order to obtain conclusions concerning the GPx enzyme as a biomarker of oxidative stress and objective therapeutic indications for reducing the level of oxidative stress and respectively cellular oxidation