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The N-terminal amino group of glycine, the imidazole side chain of histidine, and the deprotonated amide nitrogen of the Gly-His peptide bond together coordinate the copper(II) ion in a square-planar (or square-pyramidal with axial water) geometry

In contrast, the levels of calcium channel-related proteins Mitochondrial Calcium Uniporter (MCU), Sodium Calcium Lithium Exchanger (NCLX), and Leucine Zipper and EF-Hand Containing Transmembrane Protein 1 (LETM1) were reduced only in PACS patients with neuropsychiatric symptoms

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