Both peptides are studied in the context of connective tissue biology, but their molecular mechanisms are complementary, not identical
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No specific labeling by NbLumSyt1, fused to a GFP-tag, was observed after incubating neurons from Syt1 knockout (KO) mice 18 , confirming specificity as also further confirmed by immunoprecipitation experiments, in which endogenous Syt1 was enriched from wildtype (WT) but not from Syt1-KO brain extracts ( Fig
Most importantly, these findings indicate that protein and lipid oxidation products can be used as potential diagnostic markers in AR (139)
Data from a study showed that 4-HNE/protein adduct levels were higher in OA osteoblasts than in normal osteoblasts and when OA osteoblasts were treated with hydrogen peroxide [93]
To address the critical issue of BBB permeability, studies using [H]Dihexa and [C]inulin in rats revealed that Dihexa avidly concentrated in all examined brain regions including the prefrontal cortex, hippocampus, hypothalamus, striatum, thalamus, midbrain, brain stem, and cerebellum, compared to blood
