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Healthy control subjects were recruited through the use of posters advertising the opportunity to participate in a neuroimaging study involving tracking outcomes following FEP

GST non-enzymatic functions GSTs are also implicated as modulators of signal transduction pathways implicated in cell survival and apoptosis, where they control the activity of members of the mitogen-activated protein kinase (MAPK) family 24,25

Thoma ME, McLain AC, Louis JF, King RB, Trumble AC, Sundaram R, et al

Further research should address whether decreasing RBC number or a change in noncanonical functions of RBCs (such as control of NO metabolism and redox regulation) may account for alterations of RBC-PLT interactions and thrombotic and hemostatic complications in anemia

Theoretical concerns exist with anticoagulants, blood pressure medications, and immunosuppressants