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The results are consistently positive and the mechanistic data is compelling, but as of 2026 there are no completed Phase 3 human randomized controlled trials

"Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis"

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Further research, including controlled studies with proper single-compound comparison groups, is needed to validate any combined effect

The FDAs final stance on allowing compounding of these substances will hinge on how the discussions evolve during the upcoming meeting

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