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The pharmaceutical material should flow freely into the space without any resistance or significant discomfort to the patient

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A small RCT (n=21) found that inhaled glutathione (600 mg twice daily for 3 months) modestly improved some pulmonary function parameters (Griese et al., Am J Respir Crit Care Med, 2004) [47]

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Dupilumab is also associated with an increased risk of oral herpes (cold sores)

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