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As Schwann cells are the most abundant glial cells in the peripheral nervous system, are major producers of both neurotrophins, and acquire a repairing phenotype after a nerve is damaged [68], it is plausible to hypothesize that the effects of cortistatin in neurotrophins are exerted through these cells

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Historical Background and Scientific Context Scientific interest in peptide fragments increased substantially as advances in peptide chemistry enabled researchers to identify and synthesise increasingly specific molecular structures

It also aids in the maintenance of proper blood flow and oxygen supply to the bodys organs