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Cancer Res 67(9):4210-4218, 2007

Restriction of methionine, first proposed in 1959 388 , collapses one-carbon metabolism and synergizes with radiotherapy or immunotherapy

BPC-157 is a synthetic 15-amino-acid pentadecapeptide (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val), a partial sequence of the Body Protection Compound found in gastric juice

Optional: 48 mg of dexamethasone may be added to increase half life of the bupivacaine

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NICOTINAMIDE (NAM), NAD+ PRECURSOR: The NAMPT salvage pathway that converts nicotinamide to NAD+ represents the major route to NAD+ biosynthesis in mammals