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Mice that were given an mRNA vaccine expressing pre-fusion SARS-CoV-2 S protein developed neutralizing antibodies and S-protein-specific CD8 T cell responses that were protective against lung infection without evidence of immunopathology 116 , and neutralizing mAbs against the RBD of the S protein of SARS-CoV-2 reduced lung infection and cytokine release 117

In addition, we carried out pilot studies to isolate hemeHPX-binding proteins (i.e., putative receptors and other biologically relevant HPX-interacting proteinsan interactome) using hemeHPX affinity chromatography of whole-cell extracts from three different human cell types: human promyelocytic HL-60 cells, human hepatoma HepG2 cells, and freshly isolated, plated human hepatocytes

The method of claim 7, wherein said one or more HGF mimics is administered with a pharmaceutically acceptable excipient

This product is designed for laboratory research and investigational purposes only

Keep reconstituted solutions refrigerated (2-8C) only