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Individual factors like tolerance, body weight, and overall health influence the precise danger threshold, but consistently high BACs markedly increase the risk of death

Moreover, serotonin produced in the gut cannot cross the blood-brain barrier, and therefore, does not contribute directly to central neurotransmission

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Spine 29 , 26792690 (2004)

Gordon: Uh, [laughs] you know, so your influence is huge