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Dysregulation of axonal sodium channel isoforms after adult-onset chronic demyelination

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However, another study revealed that increased polyamines promoted tumor growth and progression, and inhibition of polyamine could serve as a therapeutic strategy for renal cancer (Ochocki et al., 2018)

Two major lipid peroxidation products, malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE), increase with aging and contribute to the pathogenesis of AMD 63,64,65

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