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It should be noted that nitrofurantoin followed a slower kinetic profile, characterized by RecA foci appearing at 10 min, followed by nucleoid relaxation, loss of DAPI signal, and loss of RecA foci at 30 min, while Cu 3 -TC-Pyr already showed DNA dispersal at 10 min (Supplementary Fig

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Complementary findings demonstrated that systemic immune activation via LPS in mice produced sustained reductions in novel object exploration for up to 24 h (Haba et al., 2012)

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