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As of now, these substances are also not approved for performance enhancement

In addition, elderly, obese, hypertensive and frail populations have been reported to have lower plasma L-carnitine levels 9 ( Figure 1 )

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Elevated intra-articular iron levels and altered expression of ferroptosis-related molecules such as ACSL4 and GPX4 have been associated with the severity of joint pain, cartilage damage, and functional decline ( In summary, ferroptosis is a shared pathological mechanism across multiple joint tissues in OA