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World Scientific

The biomarker clusters with increased lactate, pyruvate, alanine, and sometimes tricarboxylic acid cycle (TCA) intermediates (Figure 5, group 1), suggest dysfunction of oxidative phosphorylation or the TCA cycle

The production of NO from arginine is catalyzed by the enzyme nitric oxide synthase (NOS) via the L-arginine-NO pathway [86]

If more than four days have passed, skip the missed dose entirely and resume on your next regularly scheduled day

EVs also mediate indirect toxicity by transferring miRNAs (e.g., miR-29b and miR-7) from astrocytes to neurons, thereby suppressing neuroprotective factors and disrupting synaptic integrityeffects that are potentiated by morphine [152, 153]

10.1016/S1473-3099(14)70780-7 Lancet Infect