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The evidence base is almost entirely preclinical: rodent models consistently show accelerated tissue repair, gut healing, and neurological protection, but human RCT data remains largely absent

Different salt forms have different effective potencies, and unlabeled salt forms introduce dosing uncertainty

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The prevalence of depression is greater in those who follow a Western dietary pattern, which includes sugary and fatty meals, refined grains, fried and processed foods, red meat, high-fat dairy products, and low intake of fruits and vegetables (242, 243)

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Some users report noticing subtle improvements in pain and inflammation within the first few weeks