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In modern life, staying up late, prolonged stress, environmental pollution, an unbalanced diet, or frequent exposure to UV rays can all increase oxidative stress

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Martn-Snchez F, Diamond C, Zeitler M, Gomez A, Baroja-Mazo A, Bagnall J, et al

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Treatment involves nonpharmacologic approaches (e.g., olfactory training, cognitive rehabilitation, and physical therapy) and pharmacologic agents (e.g., gabapentinoids, tricyclic antidepressants, and experimental treatments such as N -acetylcysteine and guanfacine)

(5) Based on mechanistic strength and delivery compatibility, ICA + PLGA scaffold and curcumin + tFNA nanodelivery system are proposed as the most promising translational candidates