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PLoS ONE 9(8):e103929 Burstein R, Jakubowski M, Garcia-Nicas E et al (2010) Thalamic sensitization transforms localized pain into widespread allodynia

To investigate this rebound period, mice were exposed to CS for 5 hours and then allowed to rest in a room receiving filtered air for 0, 2, 4, 8, or 16 hours

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Moreover, chronic LPS exposure has been shown to lower the seizure threshold, activate brain glial cells, and induce depressive-like behaviors in animal models (Chen et al., 2025)

63 , e12407 (2017)

Complete rest often proves counterproductive for tendon and muscle problems, but continuing aggravating activities impairs healing regardless of peptide support