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Theoretical calculations The geometry of a metal complex was determined using density-functional theory calculations with the Gaussian software package

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(PubMed) Wang B, Yu M, Zhang R, Chen S, Xi Y, Duan G

In contrast, most of the other MPTP and rotenone-induced cellular and animal models are acute, and the concentrations of rotenone or MPTP used are more than sufficient to completely inhibit complex I [17, 35]