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A 2015 research review linked taking too much B12 to acne, rosacea, vitiligo, and atopic dermatitis

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Central sensitization: implications for the diagnosis and treatment of pain

When NNMT is overactive as it tends to be in fat tissue, and increasingly with age and obesity it siphons off the very raw material your cells need to keep NAD+ topped up

"Lowering homocysteine with B vitamins has no effect on biomarkers of bone turnover in older persons: a 2-y randomized controlled trial"

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