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In TCM, Gegen ( Pueraria lobata (Willd.) Ohwi) is used to treat diarrhea due to spleen deficiency, while puerarin, the main active ingredient of Gegen, can regulate the expression of CRF1, p-ERK/ERK, and sealin, enhance the proliferation of colonic epithelial cells, repair the colonic mucus barrier, and improve the abdominal pain and diarrhea caused by IBS-D (Wang et al., 2021)

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Scanning electron microscopy analysis reveals that hairs from GHK-Cu-treated models show more regular cuticle structure, increased cortical density, and improved overall fiber integrity

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If that is so, understanding the process of fungal differentiation, per se, could be useful in designing apoptosis inducers for the development of antifungal as well as anticancer therapies

doi: 10.1016/j.jconrel.2024.10.062 8 Moreno-YruelaCFierzB