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Nitric oxide (NO) is well known for its properties as a vasodilatory agent and also plays an important role in BBB signal regulation and autocrine activity

5-HTP, a precursor to serotonin, is one of the bigger names youll see, but we hesitate to recommend it because 5-HTP can be toxic, causing serotonin syndrome in high doses

Biochim Biophys Acta 1411:334350