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Ryan G, Briscoe TA, Jobe L
Black PN, DiRusso CC
Upon its accumulation and phosphorylation, HIF-1 dimerizes with HIF- (constitutively expressed nuclear proteins), enters the nucleus, and promotes the transcription of hypoxia response elements (HRE)-containing target genes involved in energy metabolism, erythropoiesis, vascular remodelling, and other processes (Fig

Water/Aqua/Eau, Tetrahexyldecyl Ascorbate (vitamin C/antioxidant), Dimethicone (silicone/emollient), Glycerin (humectant), C912 Alkane (solvent), Ascorbyl Glucoside (vitamin C/antioxidant), Silica (texture enhancer), Pyrus Malus (Apple) Fruit Extract (plant extracts/antioxidant), Hydrogenated Lecithin (emollient), Polyglyceryl6 Polyricinoleate (emulsifier/suspending/dispersing agent), Acrylates/C1030 Alkyl Acrylate Crosspolymer (texture enhancer), Xanthan Gum (texture enhancer), Glutathione (antioxidant), Ergothioneine (antioxidant), Oryza Sativa (Rice) Bran Extract (plant extracts/antioxidant), Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer (suspending/dispersing agent), Cetyl Alcohol (emollient), Caprylyl Glycol (humectant), Lysine Carboxymethyl Cysteinate (antioxidant), CocoCaprylate/Caprate (emollient), Tocopherol (vitamin E/antioxidant), Sodium Citrate (pH adjuster), Sodium Phytate (chelating agent), Hexylene Glycol (humectant), Ethylhexylglycerin (humectant), Helianthus Annuus (Sunflower) Extract (plant extracts/antioxidant), Urea (humectant), Mannitol (humectant), Caprylic/Capric Triglyceride (emollient), Sodium PCA (humectant), Rosmarinus Officinalis (Rosemary) Leaf Extract (plant extracts/antioxidant), Polysorbate 60 (emulsifier), Sorbitan Isostearate (emulsifier), Trehalose (humectant), Ascorbic Acid (vitamin C/antioxidant), Glucose (humectant), Vanilla Planifolia Fruit Extract (plant extracts/antioxidant), Polyquaternium51 (filmforming agent), Triacetin (solvent), Sodium Hyaluronate (humectant), Phenoxyethanol (preservative)

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