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Therefore, our results could be generalised to these patients

Biofactors 49, 875886

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Specifically, we observed an upregulation of Glp1r (encoding glucagon-like peptide-1 receptor, GLP-1R), Htr4 (encoding 5-HT4 receptor), and Ntsr1 (encoding neurotensin receptor 1, NTR1)

Of these, eight CYP enzymes participate in cholesterol metabolism (CYP7A1, CYP27A1, CYP46A1, CYP11A1, CYP51A1, CYP39A1, CYP8B1 and CYP7B1), but CYP51A1 is the only one involved in the de novo synthesis of cholesterol

The same reconstitution approach applies for either route, but users often dose lower or less often than the unmodified forms