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Common experiences after the first injection include: Mild soreness or redness at the injection site (usually resolves within 12 days) Slight improvement in energy levels or mood No immediate noticeable change (particularly common if deficiency is severe) Rarely, mild side effects such as headache or dizziness Some patients report their urine becoming brighter or more intensely coloured following injection, which occurs because excess B12 is excreted renally
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PubMed Holst, J.J., & Rosenkilde, M.M
This is a risk, not just a benefit
While large-scale human clinical trials are ongoing, preclinical and anecdotal evidence is strong
Timed, subacute MPTP administration disrupted the intestinal barrier, immune status, and gut microbiota after the first dose
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