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In Phase I metabolism, paracetamol is primarily metabolized by the enzyme CYP2E1, resulting in the formation of a toxic metabolite called N-acetyl-p-benzoquinonimine (NAPQI)

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doi: 10.3748/wjg.v23.i33.6164 262 GongXLiuXChenCLinJLiAGuoKet al

Additionally, ALA enhances the conversion of carbohydrates into energy, limiting their conversion into fats

Cell-culture (3T3-L1 adipocytes) 5-Amino-1MQ at 30 M strongly reduced 1-MNA levels in mouse fat cells, confirming NNMT inhibition (Neelakantan et al., Biochemical Pharmacology, 2018)

Weiss FD, Calderon L, Wang YF, Georgieva R, Guo Y, Cvetesic N, et al