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It has been demonstrated that hyperglycemia reduces LPS-induced neutrophil degranulation, which in turn reduces the release of myeloperoxidase and elastase from azurophilic granules

FIGURE 7 4 Discussion The deleterious effects of smoking on male gonadal function and fertility are well known ( PAHs are known to induce severe redox stress in cells and tissues, leading to the oxidation of nucleic acids, proteins, and lipids ( As expected, testis samples from exposed animals showed activation of DNA repair machinery, including the 8-oxoguanine glycosylase (OGG1), a base excision repair enzyme responsible for the recognition and removal of 8-OHdG, histone H2A variant, H2AX and PARP-1

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The immune response in multiple sclerosis