Clinical studies performed by using nerve growth factor show that a single injection into normal individuals produces both mechanical and thermal hypersensitivity at the site of injection, which is rapid, reaching a maximum by 21 d and 3 d, respectively (39)
Because it hasn't gone through the rigorous testing required for medical use, its safety for humans is largely unknown
Mol Cancer Ther 7(5):1130-1139, 2008
The injection may deliver the signal perfectly
Monami M, Nreu B, Scatena A, Cresci B, Andreozzi F, Sesti G, et al
Epigenetic and Cellular Reprogramming: By blocking NNMT-mediated methylation of nicotinamide, preserves NAD salvage pathway activity, increases SIRT-1 signaling, reduces histone deacetylation, and promotes metabolic reprogramming toward oxidative phosphorylation and glycolysis balance, supporting tissue repair and energy homeostasis 1-4