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The weight loss is driven by a ~25% increase in whole-body fat oxidation and resting energy expenditure

Certain health conditions such as intestinal or stomach problems, poor nutrition, cancer, HIV, pregnancy, old age, veganism, and alcoholism can cause vitamin B12 deficiency

However, clinical trials in humans have demonstrated mixed results

Adjustment Criteria: Decisions on treatment changes depend on the initial deficiency level, neurological symptoms, and how well the patient responds

Risks and Side Effects: What to Watch For Tesamorelins side effect profile is well-documented from the Phase 3 trials