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After withdrawal of a blood sample, the mice were allowed to recover for at least 1 day and the average running wheel activity over the next two days was taken as baseline value

Fu S, Deng H, Bertolini I, Perego M, Chen ES, Sanseviero E, et al

**Final Mix:** Continue stirring for another minute, ensuring all ingredients are fully integrated

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The bottom line on human data: promising signals, no randomized controlled trials, and no long-term safety data in humans

Furthermore, our single-cell mass cytometry approach was limited to ~40 proteins, capping the number of metabolic pathways we could interrogate simultaneously