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Most published GHK-Cu research uses the copper-bound form, since the copper coordination is what gives the molecule much of its studied activity
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Zincs role in reducing oxidative stress and modulating inflammatory pathways further suggests its potential to delay or reduce the progression of specific age-related diseases, including age-related macular degeneration, diabetes, depression, atherosclerosis, and impaired wound healing
[DOI] [PubMed] [Google Scholar] 127.Nagy HM, Paar M, Heier C, Moustafa T, Hofer P, Haemmerle G, et al
In accordance with the latter report, phosphorylated ERK was decreased in EpCAM CRISPR/Cas9-mediated knockout cells, suggesting EpCAM augments integrin-mediated signaling [119]
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