For drug-induced hepatitis: 12001800 mg, once daily, intravenous drip, for 1430 days
Ubbink, 1994) but also in healthy subjects (Lussier-Cacan et al, 1996
The discovery of thyroid replacement therapy
Tissue inhibitor of metalloproteinase-1 (TIMP-1), a cytokine produced by neuroprotective astrocytes, has been shown to stimulate A clearance and improve cognitive function in AD mice 135
Important safety considerations include: Inform your GP about all supplements you are taking Avoid self-treating suspected deficiency without medical assessment, as supplementation can mask underlying pernicious anaemia whilst allowing neurological damage to progress Do not start high-dose folic acid supplements before B12 deficiency is excluded, as this can worsen neurological damage Check for interactions if taking medications such as metformin, chloramphenicol, or proton pump inhibitors Monitor response through appropriate blood tests if treating deficiency Pregnant women, individuals with Leber's disease (a rare hereditary eye condition), and those with cobalt allergy should consult healthcare professionals before supplementing
McIlroy DJ et al (2014) Mitochondrial DNA neutrophil extracellular traps are formed after trauma and subsequent surgery