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Because IGFBP-3 also carries IGF-1, when IGF-1 is administered on its own, the carrier IGFBP-3 saturates with IGF-1 displacing IGF-2 and thus augments its free circulating concentration
Similarly, in rice ( Oryza sativa ), the OsGLR3.1 knockout mutant plants also show a short root, and the further experiments indicate that OsGLR3.1 positively regulates cell proliferation and survival in the root apical meristem (Li et al., 2006)
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Do not give FIRDAPSE to other people, even if they have the same symptoms that you have
However, this mechanism requires the presence of susceptible substrates