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The current understanding of SJS/TEN pathogenesis is summarized in Fig

Alpha-lipoic acid protects against renal ischaemia-reperfusion injury in rats

PLoS ONE 7 , e35192 (2012)

Physiological functions of eryptosis Eryptosis: physiological role Eryptosis is a part of the body defense system that leads to the shortening of the lifespan of damaged erythrocytes, subsequently removing them from circulation (Fig

[113] Other studies have noted increased survival in malignant melanoma [114] and patients with metastatic disease

These include everolimus, a mechanistic target of rapamycin complex 1 inhibitor that modulates mitochondrial turnover, and idebenone, which bypasses complex I defects to directly transfer electrons