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High doses of methylcobalamin are generally well tolerated but should still be used cautiously

These letters appear to be indiscriminate cost saving initiatives and are being sent out as individual practice directives and not that of the CCG (Clinical Commissioning Group)

In a Phase III study, 82.3% of patientswho had residual anemia after anti-C5 treatmentsaw a sustained increase in hemoglobin levels even without transfusions compared with 0% of those who stayed on anti-C5 treatments

Boehncke S, Fichtlscherer S, Salgo R, Garbaraviciene J, Beschmann H, Diehl S,

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