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Enhancement of SAMe levels permit it to act as the cofactor of COMT, which prevents catalysis in the first step in a degradation pathway of the catecholamine neurotransmitters, and can therapeutically decrease COMT enzyme activity [183]

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however, the molecular crosstalk between ferroptosis and autophagy pathways is not fully understood, and the molecular mechanism by which autophagy affects ferroptosis needs further exploration [36]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Liu Q, Jia Z, Duan L, Xiong J, Wang D, Ding Y: Functional peptides for cartilage repair and regeneration

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