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C-Met is expressed by highly autoreactive encephalitogenic CD8+ cells
Extreme purging, even if it would eventually resolve, may not be acceptable depending on your circumstances
To confirm that interface IV is essential for c-MET activation, we introduced Y673A mutation into HGF to disrupt this interface, and showed that HGF Y673 mutant has a great deficiency in binding to c-MET as well as promoting c-MET activation (Fig
Ding X, Zhao H, Li Y, Lee AL, Li Z, Fu M
The final model of DPA-bound Pa DHDPR had R work and R free values of 16.0% and 19.5%, respectively, whereas the final model of NADPH/DPA-bound Pa DHDPR had R work and R free values of 18.7% and 25.7%, respectively