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Chaichit S, Sato T, Yu H, Tanaka Y-K, Ogra Y, Mizoguchi T

This sophisticated regulation prevents both copper deficiency and copper toxicity at the cellular level

Hampel H, Mesulam MM, Cuello AC, Farlow MR, Giacobini E, et al

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We also observed that inflammasome activation by sUA+LPS is NLRP3- and MyD88-dependent, since macrophages from Nlrp3 / and Myd88 / mice failed to produce IL-1 levels comparable to Wild-type mice (WT) (Fig