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Individuals with significant body weight to lose, typically those with a BMI that qualifies for GLP-1 therapy and who have 30% or more body weight to lose, may benefit from the more aggressive metabolic intervention this combination provides

Its important to note that weight loss is ultimately contingent on burning more calories than you consume in a day

The theoretical extension of this rationale to retatrutide is scientifically plausible but remains exploratory

Additionally, there was a decrease in the body mass index (BMI) and the patients reported that their menstrual cycles became more regular and that their hirsutism diminished (136)