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The investigation conformed to the Guide for the Care and Use of Laboratory Animals published by the National Academies Press (8th edition, revised 2011)

Across preclinical anxiety models, there was a consistent enrichment of pathogenic or dysbiosis-associated bacteria

By contrast, the areas that had been treated with BPC 157 presented almost completely spared mucosa with very small pale areas and no gross mucosal defects, a colon segment of normal diameter, and few adhesions (Table 3, Figure 20)

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More study results are expected in 2026, and it could potentially be approved as early as 2027