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H 2 S is primarily generated from L-cysteine, obtained through dietary intake, extraction from endogenous proteins, or endogenous synthesis via the transsulfuration of serine by L-methionine, a process occurring within the transsulfuration pathway

Front Biosci 15:2534

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In support of this is the finding that overexpression of GS failed to increase GSH level whereas overexpression of GCL increased GSH level [49]