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c-MET pathway has been reported to be associated with several other signaling pathways in HNSCC

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Two estimands were employed: the trial product estimand, which evaluated treatment effects assuming perfect adherence to the assigned regimen, and the treatment policy estimand, which included all randomized participants regardless of adherence

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Moreover, the small sample size and short duration of the trials completed to date have also been a strong limitation in the identification of effective therapeutic strategies

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