Che M., Wang R., Li X., et al., Expanding Roles of Superoxide Dismutases in Cell Regulation and Cancer, Drug Discovery Today 21, no
In vivo reversal of glutathione deficiency and susceptibility to in vivo dexamethasone-induced apoptosis by N-acetylcysteine and L-2-oxothiazolidine-4-carboxylic acid, but not ascorbic acid, in thymocytes from gamma-glutamyltranspeptidase-deficient knockout mice
This suggests an indirect regulatory mechanism possibly involving interactions with other transcription factors, such as ATF4
NRF2 regulates the transcription of genes coding for antioxidant proteins and thereby protects against oxidative damage
PBMCs from G6PD-d infants showed no difference in IL-10 secretion compared to controls following toll-like receptor (TLR) stimulation 52
Vitamin C helps regenerate other antioxidants, especially glutathione, which makes it one of the more accessible, natural ways to boost glutathione levels through diet and supplementation