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In an uncontrolled trial, 19 men with infertility had improvement in sperm morphology and function after 90 days of treatment with pine bark extract at 200 mg per day

[DOI] [PubMed] [Google Scholar] 34.Drmic D, Kolenc D, Ilic S, Bauk L, Sever M, Zenko Sever A, et al

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In addition, a deficiency of vitamin B12 can cause facial signs such as hyperpigmentation (dark spots), vitiligo (white patches where skin loses color), or angular stomatitis (inflammation at the corners of the mouth)