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BMP4 expression in the oesophageal mesenchyme is first upregulated by pro-inflammatory agents such as acid and bile

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This implies the initial rupture of the BBB for cellular migration

It has been shown that MSCs increase tensile strength through a macrophage-dependent mechanism in wound healing in old mice, restoring the strength levels seen in younger adult mice (Lee et al., 2013)

Thymosin beta4 promotes angiogenesis, wound healing, and hair follicle development

Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II