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These results also indicate a change in the expression of synaptic dopamine receptor proteins (D1 and D2), a decreased in serotonergic receptors (5-HT1A and 5-HT2A), metabotropic GABA-B, and muscarinic receptors (18)

PINK1 mutations in humans lead to mitochondrial defects and respiratory chain abnormalities (Piccoli et al., 2008)